Francesca Tonelli Selected Research

rab GTP-Binding Proteins

11/2018	A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain.
1/2018	Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.
11/2017	Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.
1/2016	Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.

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Francesca Tonelli Research Topics

Disease

15	Parkinson Disease (Parkinson's Disease) 12/2021 - 01/2016
6	Prostatic Neoplasms (Prostate Cancer) 06/2013 - 10/2010
4	Neoplasms (Cancer) 04/2013 - 01/2012
3	Breast Neoplasms (Breast Cancer) 05/2011 - 10/2010
2	Bone Diseases (Bone Disease) 01/2019 - 01/2017
2	Congenital Abnormalities (Deformity) 01/2018 - 01/2017
1	Wounds and Injuries (Trauma) 01/2017
1	Osteogenesis Imperfecta (Lobstein Disease) 01/2017

Drug/Important Bio-Agent (IBA)

15	Phosphotransferases (Kinase)IBA 12/2021 - 04/2013
7	sphingosine kinaseIBA 06/2013 - 10/2010
5	AndrogensIBA 06/2013 - 10/2010
4	Leucine (L-Leucine)FDA Link 01/2020 - 01/2016
4	rab GTP-Binding ProteinsIBA 11/2018 - 01/2016
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2018
3	Fingolimod Hydrochloride (FTY720)FDA Link 06/2013 - 10/2010
3	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 03/2013 - 02/2012
2	Protein Kinases (Protein Kinase)IBA 01/2021 - 01/2018
2	Leucine-Rich Repeat Serine-Threonine Protein Kinase-2IBA 10/2019 - 01/2016
2	Leucine-Rich Repeat ProteinsIBA 01/2018 - 01/2018
2	Collagen Type I (Type I Collagen)IBA 01/2018 - 01/2017
2	((E)- 3- amino- 5- (4- heptylphenyl)- 3- (hydroxymethyl)pent- 1- enyl)phosphonic acidIBA 06/2013 - 10/2010
2	Protein Isoforms (Isoforms)IBA 04/2013 - 09/2012
2	CeramidesIBA 09/2012 - 12/2010
2	LipidsIBA 09/2012 - 02/2012
1	AntibodiesIBA 01/2018
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2018
1	alizarinIBA 01/2017
1	ursodoxicoltaurineIBA 01/2017
1	Alcian BlueIBA 01/2017
1	CollagenIBA 01/2017
1	fluorexon (calcein)IBA 01/2017
1	SphingolipidsIBA 06/2013
1	Ether (Diethyl Ether)IBA 06/2013
1	lysophosphatidylinositolIBA 06/2013
1	4- (4- (4- chloro- phenyl)thiazol- 2- ylamino)phenolIBA 04/2013
1	SphingosineIBA 04/2013
1	fragile histidine triad proteinIBA 04/2013
1	diadenosine triphosphate (ApppA)IBA 04/2013
1	Androgen Receptors (Androgen Receptor)IBA 03/2013
1	Amino Acids FDA Link 09/2012
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 02/2012
1	Sphingosine-1-Phosphate ReceptorsIBA 02/2012
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 02/2012
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 05/2011
1	EnzymesIBA 10/2010

Therapy/Procedure

1	Therapeutics 01/2019